Wasim Zahid new PhD on Myocardial function by echocardiography for risk stratification in patients with heart disease

Wasim Zahid PhD On October 6th 2016 Wasim Zahid, MD defended his thesis at Institute of Clinical Medicine at Faculty of Medicine University of Oslo. The topic was "Myocardial function by echocardiography for risk stratification in patients with heart disease". The trial lecture topic was "The prognostic and diagnostic value of troponins in acute and stable coronary heart disease". On the picture from left: 2. opponent professor Henrik Schimmer, 1. opponent professor Leila Elif Sade, dr Wasim Zahid, professor Thor Edvardsen and professor Erik Fosse.

Abstract: Ultrasound examination of the heart (echocardiography) may provide more accrate information about a patient’s heart disease, and the course it may take in the future. When a coronary artery becomes very narrow due deposition of lipids, calcium and cell debris (a process known as atherosclerosis), a patient may suffer acute myocardial infarction, and the myocardium is damaged. There are different types of infarcts. Some are large (with considerable myocardial damage), are caused by occluded arteries, while others are smaller, and caused by merely narrow vessels. Large infarcts and occluded arteries have worse prognosis, cause more symptoms, and put patients at higher mortality risk.
The electrocardiogram (ECG) plays a central role in the diagnosis of acute myocardial infarction, but may not always distinguish between the different types of infarcts. There is therefore a need for diagnostic and prognostic tools that can provide more accurate information concerning severity, so that patients at higher risk can be given priority for treatment. Our studies have shown that echocardiography can distinguish between patients with large and small infarcts, narrow and occluded arteries, and identify patients at higher risk of dying following infarction.
We have also studied the role of echocardiography in patients with carcinoid disease. This is a type of cancer disease where the tumors produce specific substances which may affect and damage distant organs, including the heart. Our studies show that echocardiography and certain biomarkers may identify patients with higher mortality risk. It can be important to identify these patients, so that they can be given closer monitoring and treatment.

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