New PhD on Myocardial function and 3D motion analysis using a three-axis accelerometer during cardiac surgery

ojgOn September 1st 2017 Ole-Johannes Holm Nielsen Grymyr dended his thesis at Faculty of Medicine, University of Oslo. The commission was 1.opponent Michael Broomé, ECMO Centre, Karolinska Institutet, Stockholm, Sweden, 2. opponent Professor Truls Myrmel, Institutt for klinisk medisin, Universitetet i Tromsø - Norges arktiske universitet, Norway and Professor II Theis Tønnessen, Institutt for klinisk medisin, Universitetet i Oslo. Professor II Johan Ræder, Institutt for klinisk medisin, Universitetet i Oslo led the dissertation. Abstract: Complications to heart surgery can be detected instantly with accelerometers placed on the heart wall. Myocardial ischemia and heart failure are the most frequent complications after heart surgery. These complications can be detected in real time with motion sensors such as accelerometers as heart motion is linked to heart function. Instant and distinct changes in myocardial contraction are found if the blood-flow is reduced. Previously work has shown that a 3-axis accelerometer placed on the heart allows earlier detection of this complication than routine measures like invasive blood pressures and electrocardiograms.

The aim in this thesis was to develop and test a simplified accelerometer 3D motion analysis to increase the practicability of the method in the clinical routine. The accelerometer was tested for detection of myocardial ischemia and for heart function assessment in experimental and clinical models during both open and closed chest conditions with different sensor placements on the heart. The 3D method was compared to routine hemodynamic monitoring and echocardiography.

The results in this thesis show that the accelerometer 3D method provided important information of heart contraction and function in real time. The more user-friendly 3D method can be used for postoperative real time monitoring of both left and right ventricular function, for evaluation of medical treatment and for the detection of myocardial dysfunction.

The 3D method makes accelerometers more suitable for clinical use, and miniaturization of the technology has recently made it possible to incorporate the sensor into temporary pacemaker wires which may be routinely placed during heart surgery. In the future accelerometers may provide lifelong surveillance of heart function by wireless transmission to smartphones.

MedTech Test Facility

OUS Test FacilityVisit the web page of the MedTech Test Facility at Oslo University Hospital. The Test Facility is a professional gateway for companies with new high tech equipment in need for early phase clinical trials.

Contact

Oslo Medtech

OMTThe Intervention Centre and Oslo University Hospital are founding members of Oslo Medtech, and work actively with Oslo Medtech to develop medtech industry in Norway.

Twitter

IVS Twitter

Information in Norwegian

English is the main language in this web portal. Some information is also available in Norwegian Norwegian text

Donations to Medical Research

The Interventional Centre receives donations to medical research. Questions related to donations can be sent to head of department professor Erik Fosse.

HONCode

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.

Add This

Bookmark and Share

Annual Report 2016

Annual Report 2016

Annual Report 2015

Annual Report 2015

Annual Report 2014

2014

Annual Report 2013

Annual Report 2013

Annual Report 2012

2012

Annual Report 2011

Annual Report 2011

Annual Report 2010

Annual Report 2010

Roadmap Norwegian Research Infrastructure

Norwegian Roadmapp for Research Infrastructure

Annual Report 2009

Annual report 2009

Annual Report 2008

Annual Report 2008

Annual Report 2007

Annual Report 2007

New book about the Interventional Centre

New book about the Interventional Centre

Author: Erik Fosse
Publisher: Det Medisinske Selskap 2007
Price: 180 kr
Online order
Also sold in Bookstores

RSS Feeds